Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.52 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664868 | 0.97 | STK17B (0.55) | STK17BSTK17AGRIN1GRIN2BTDP1 | |
| SCHEMBL30787994 | 0.84 | CA1 (0.63) | CA1CA2LMNAHTT | |
| SCHEMBL22546955 | 0.84 | CA1 (0.63) | CA1CA2LMNAHTT | |
| SCHEMBL2991645 | 0.83 | MAPK1 (0.53) | STK17BSTK17ATDP1DRD2CA1 | |
| SCHEMBL13664796 | 0.82 | MEN1 (0.40) | STK17BSTK17AGRIN1GRIN2BLMNA | |
| SCHEMBL29894737 | 0.82 | EGFR (0.51) | STK17BSTK17ALMNAHTTIDO1 | |
| SCHEMBL8271413 | 0.81 | TDP1 (0.54) | STK17BSTK17ATDP1DRD2CA1 | |
| SCHEMBL14830020 | 0.80 | PYGL (0.53) | STK17BSTK17AGRIN1GRIN2BTDP1 | |
| SCHEMBL29894690 | 0.80 | EGFR (0.46) | STK17BSTK17ATDP1DRD2CA1 | |
| SCHEMBL29894718 | 0.80 | EGFR (0.50) | STK17BSTK17AGRIN1GRIN2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |