Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123600 | 0.89 | HTT (0.53) | HTTMAPTCCR6PAX8LMNA | |
| SCHEMBL19879681 | 0.89 | CCR6 (0.49) | HTTMAPTCCR6PAX8CA14 | |
| SCHEMBL9772169 | 0.88 | MAPT (0.55) | HTTMAPTCCR6PAX8LMNA | |
| SCHEMBL9766179 | 0.88 | CCR6 (0.53) | HTTMAPTCCR6PAX8LMNA | |
| SCHEMBL9766146 | 0.87 | CCR6 (0.52) | HTTMAPTCCR6PAX8LMNA | |
| SCHEMBL30135568 | 0.87 | HTT (0.51) | HTTMAPTCCR6PAX8LMNA | |
| SCHEMBL30135570 | 0.87 | HTT (0.51) | HTTMAPTCCR6PAX8LMNA | |
| SCHEMBL4927806 | 0.87 | HTT (0.51) | HTTMAPTCCR6PAX8LMNA | |
| SCHEMBL10647524 | 0.86 | CCR6 (0.51) | HTTMAPTCCR6PAX8LMNA | |
| SCHEMBL20467679 | 0.86 | CCR6 (0.51) | HTTMAPTCCR6PAX8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |