SCHEMBL1366489

SCHEMBL1366489

O=C(CCCCl)OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
MAPK1 P28482 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
TDP1 Q9NUW8 3/20 0.50
KMT2A Q03164 2/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
LMNA P02545 2/20 0.49
POLB P06746 2/20 0.49
MEN1 O00255 1/20 0.49
MAPT P10636 1/20 0.49
HTT P42858 1/20 0.47
EPHX2 P34913 1/20 0.46
HCAR2 Q8TDS4 1/20 0.46
NOTUM Q6P988 1/20 0.46
CDC25B P30305 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1363999 0.95 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL1364176 0.93 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL1366401 0.93 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL1364948 0.93 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL1365781 0.93 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL523412 0.89 ALDH1A1 (0.63) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL3963428 0.89 ALDH1A1 (0.68) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL18673 0.89 ALDH1A1 (0.68) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL10918679 0.88 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL7825313 0.88 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112262156-B Anti-HER 2 antibodies 新加坡科技研究局 2024-07-05 CN disclosed
CN-117209502-A Inhibitors of BTK and mutants thereof 广州麓鹏制药有限公司 2023-12-12 CN disclosed
CN-111741959-B Inhibitors of BTK and mutants thereof 广州麓鹏制药有限公司 2023-09-05 CN disclosed
CN-116621860-A Bcl-2 inhibitors 广州麓鹏制药有限公司 2023-08-22 CN disclosed
CN-116425771-A Condensed heterocyclic derivatives as Bcl-2 inhibitors for the treatment of neonatal diseases 广州麓鹏制药有限公司 2023-07-14 CN disclosed
CN-112546244-B Fibroblast growth factor receptor 2 specific peptide reagents and methods 密执安州立大学董事会 2023-07-04 CN disclosed
CN-111511748-B Bcl-2 inhibitors 广州麓鹏制药有限公司 2023-05-02 CN disclosed
CN-111448198-B Condensed heterocyclic derivatives as Bcl-2 inhibitors for the treatment of neonatal diseases 广州麓鹏制药有限公司 2023-02-03 CN disclosed
CN-113939292-A Inhibitors of BTK and mutants thereof 广州麓鹏制药有限公司 2022-01-14 CN disclosed
CN-112546244-A Fibroblast growth factor receptor2 specific peptide reagents and methods 密执安州立大学董事会 2021-03-26 CN disclosed
EP-1774410-A1 CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS Canon Kabushiki Kaisha (JP) 2007-04-18 EP disclosed
US-20070073006-A1 Polyhydroxyalkanoate having vinyl group, ester group, carboxyl group, and sulfonic group, and method of producing the same CANON KABUSHIKI KAISHA (JP) 2007-03-29 US disclosed
EP-1758948-A2 POLYHYDROXYALKANOIC ACID HAVING VINYL, ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR Canon Kabushiki Kaisha (JP) 2007-03-07 EP disclosed
US-20060194071-A1 Developer carrying member and development apparatus CANON KABUSHIKI KAISHA (JP) 2006-08-31 US disclosed
US-20050287484-A1 Resin-coated carrier for electrophotographic developer CANON KABUSHIKI KAISHA (JP) 2005-12-29 US disclosed
WO-2005121207-A2 POLYHYDROXYALKANOATE HAVING VINYL GROUP, ESTER GROUP, CARBOXYL GROUP, AND SULFONIC GROUP, AND METHOD OF PRODUCING THE SAME CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121904-A1 CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121204-A2 POLYHYDROXYALKANOIC ACID HAVING VINYL, ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121205-A2 POLYHYDROXYALKANOATE HAVING ESTER GROUP, CABOXYL GROUP, AND SULFONIC GROUP, AND METHOD OF PRODUCING THE SAME CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121208-A1 POLYHYDROXYALKANOIC ACID HAVING ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed