Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.66 |
| ▸ | AHR | P35869 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560962 | 0.83 | KDM4E (0.65) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL7030842 | 0.81 | KCNH2 (0.68) | KDM4EAHRNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL6857835 | 0.81 | KDM4E (0.68) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL30168106 | 0.81 | KDM4E (0.68) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL13744783 | 0.81 | MAPT (0.60) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL27947376 | 0.81 | MAPT (0.54) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL585270 | 0.80 | KDM4E (1.00) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL29502916 | 0.80 | KDM4E (1.00) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL1006030 | 0.79 | MAPT (0.67) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL2774740 | 0.79 | MAPT (0.72) | KDM4EAHRMAPTNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |