Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.65 |
| ▸ | AHR | P35869 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664957 | 0.83 | KDM4E (0.66) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL19877326 | 0.83 | LMNA (0.51) | KDM4ENPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL19890164 | 0.81 | LMNA (0.49) | KDM4ENPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL6857835 | 0.75 | KDM4E (0.68) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL30168106 | 0.75 | KDM4E (0.68) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL13744783 | 0.75 | MAPT (0.60) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL10105364 | 0.74 | OXER1 (0.52) | HTTLMNA | |
| SCHEMBL585270 | 0.74 | KDM4E (1.00) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL29502916 | 0.74 | KDM4E (1.00) | KDM4EAHRMAPTNPC1KMT2A | |
| SCHEMBL1006030 | 0.73 | MAPT (0.67) | KDM4EAHRMAPTNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873331-B1 | BENZOFURAN CARBOXAMIDES AND SULPHONAMIDES | DARWIN DISCOVERY LTD (GB) | 2002-04-03 | — | — | EP | disclosed |