Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664982 | 0.94 | JAK1 (0.41) | F10SMN1; SMN2JAK1HSD17B10KMT2A | |
| SCHEMBL13665067 | 0.92 | NPC1 (0.41) | SMN1; SMN2JAK1HSD17B10MEN1KMT2A | |
| SCHEMBL13664986 | 0.92 | F10 (0.42) | F10SMN1; SMN2JAK1HSD17B10MEN1 | |
| SCHEMBL13664967 | 0.90 | SMN1; SMN2 (0.44) | F10SMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL13664980 | 0.90 | SMN1; SMN2 (0.44) | F10SMN1; SMN2JAK1HSD17B10MEN1 | |
| SCHEMBL13664985 | 0.89 | F10 (0.42) | F10SMN1; SMN2JAK1HSD17B10MEN1 | |
| SCHEMBL13664987 | 0.89 | JAK1 (0.42) | F10SMN1; SMN2JAK1KMT2A | |
| SCHEMBL13664961 | 0.88 | SMN1; SMN2 (0.43) | F10SMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL13664971 | 0.88 | F10 (0.42) | F10SMN1; SMN2 | |
| SCHEMBL13664992 | 0.87 | SMN1; SMN2 (0.44) | F10SMN1; SMN2HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |