Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664981 | 0.94 | F10 (0.41) | JAK1F10SMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL13665068 | 0.92 | JAK1 (0.42) | JAK1SMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL13664987 | 0.90 | JAK1 (0.42) | JAK1F10SMN1; SMN2KMT2A | |
| SCHEMBL13664967 | 0.88 | SMN1; SMN2 (0.44) | F10SMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL13664980 | 0.88 | SMN1; SMN2 (0.44) | JAK1F10SMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL4318072 | 0.88 | F10 (0.45) | JAK1F10SMN1; SMN2MAPK1 | |
| SCHEMBL4318062 | 0.88 | F10 (0.45) | JAK1F10SMN1; SMN2MAPK1 | |
| SCHEMBL13664961 | 0.87 | SMN1; SMN2 (0.43) | F10SMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL13665067 | 0.86 | NPC1 (0.41) | JAK1SMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL13664986 | 0.86 | F10 (0.42) | JAK1F10SMN1; SMN2KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |
| US-7605158-B2 | Carbamoyl-type benzofuran derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-20 | — | — | US | disclosed |