Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Becocalcidiol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR known ✓ | P11473 | 11/20 | 0.76 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Becocalcidiol SCHEMBL14489149 | 1.00 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL859793 | 1.00 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL14224828 | 1.00 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL9009884 | 1.00 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL23752369 | 1.00 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL9010345 | 1.00 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL23752370 | 1.00 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL9009928 | 1.00 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL10820222 | 1.00 | VDR (0.76) | VDRCYP24A1 | |
| Becocalcidiol SCHEMBL798548 | 1.00 | VDR (0.76) | VDRCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111695-A8 | METHODS OF INCREASING EPIDERMAL SKIN THICKNESS BY TOPICAL ADMINISTRATION OF A 19-NOR CONTAINING VITAMIN D COMPOUND | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009111695-A1 | METHODS OF INCREASING EPIDERMAL SKIN THICKNESS BY TOPICAL ADMINISTRATION OF A 19-NOR CONTAINING VITAMIN D COMPOUND | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-09-11 | — | — | WO | disclosed |