Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 12/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13666616 | 0.91 | TP53 (0.52) | TP53MAPTSMN1; SMN2LMNARXFP1 | |
| SCHEMBL13666732 | 0.88 | TP53 (0.58) | TP53MAPTSMN1; SMN2LMNAKDR | |
| SCHEMBL13666876 | 0.85 | KDR (0.52) | TP53MAPTSMN1; SMN2LMNAKDR | |
| SCHEMBL13666336 | 0.85 | TP53 (0.51) | TP53MAPTLMNAKDR | |
| SCHEMBL13666358 | 0.84 | MAPT (0.52) | TP53MAPTSMN1; SMN2LMNAKDR | |
| SCHEMBL13666415 | 0.84 | KDR (0.55) | TP53MAPTSMN1; SMN2LMNAKDR | |
| SCHEMBL13666856 | 0.83 | KDR (0.53) | TP53MAPTSMN1; SMN2LMNAKDR | |
| SCHEMBL13666736 | 0.83 | ACSS2 (0.49) | TP53MAPTKDR | |
| SCHEMBL13666375 | 0.82 | TP53 (0.48) | TP53MAPTLMNAKDR | |
| SCHEMBL13666383 | 0.82 | TP53 (0.48) | TP53MAPTSMN1; SMN2LMNAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119776-A1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |