Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14549589 | 0.80 | HRH4 (0.60) | L3MBTL1ALDH1A1HRH4KMT2ACYP1A2 | |
| SCHEMBL1771402 | 0.80 | KMT2A (0.59) | L3MBTL1ALDH1A1HRH4KMT2ANPC1 | |
| SCHEMBL1772275 | 0.79 | ERN1 (0.60) | L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20149733 | 0.75 | PDE4B (0.65) | L3MBTL1ALDH1A1HRH4NPC1RAB9A | |
| SCHEMBL21717780 | 0.73 | PDE4B (0.64) | L3MBTL1ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL1372147 | 0.71 | CYP1A2 (0.75) | ALDH1A1CYP1A2SMN1; SMN2POLBALOX15 | |
| SCHEMBL10724841 | 0.70 | POLB (0.81) | L3MBTL1ALDH1A1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL4353375 | 0.70 | HRH4 (0.49) | L3MBTL1ALDH1A1HRH4KMT2ACYP1A2 | |
| SCHEMBL12311464 | 0.70 | CHRNA4 (0.54) | HRH4KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3754883 | 0.68 | HRH3 (0.66) | KMT2ACYP1A2CYP2C19NPC1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107054-A1 | Antiproliferative compounds and therapeutic uses thereof | Università Degli Studi Di Milano - Bicocca (IT) | 2009-10-07 | — | — | EP | disclosed |