Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 6/20 | 0.76 |
| ▸ | PDGFRA | P16234 | 10/20 | 0.72 |
| ▸ | KDR | P35968 | 7/20 | 0.72 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.68 |
| ▸ | KIT | P10721 | 1/20 | 0.65 |
| ▸ | AXL | P30530 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480761 | 0.88 | FGFR2 (0.78) | FGFR2PDGFRAKDRPDGFRBKIT | |
| SCHEMBL4473149 | 0.86 | FGFR2 (1.00) | FGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL27082957 | 0.86 | PDGFRA (0.82) | FGFR2PDGFRAKDRKITAXL | |
| SCHEMBL27081475 | 0.86 | PDGFRA (0.95) | PDGFRAKDR | |
| SCHEMBL30918281 | 0.86 | PDGFRA (0.82) | FGFR2PDGFRAKDRKITAXL | |
| SCHEMBL29973354 | 0.86 | PDGFRA (0.95) | PDGFRAKDR | |
| SCHEMBL7486400 | 0.86 | FGFR2 (0.84) | FGFR2PDGFRAKDRPDGFRB | |
| SCHEMBL23922772 | 0.85 | PDGFRA (0.81) | FGFR2PDGFRAKDRKITAXL | |
| SCHEMBL5824535 | 0.85 | PDGFRA (0.76) | FGFR2PDGFRAKDRKITAXL | |
| SCHEMBL4470477 | 0.85 | PDGFRA (0.74) | FGFR2PDGFRAKDRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127417-A1 | QUINOLINE DERIVATIVES AS AXL KINASE INHIBITORS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2009-10-22 | — | — | WO | disclosed |