Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 6/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13803749 | 0.87 | HDAC1 (0.36) | HDAC1 | |
| SCHEMBL12648616 | 0.86 | HDAC1 (0.39) | HRH4HRH3CNR2GBA1EPHX2 | |
| Hydrochloric Acid SCHEMBL1523923 | 0.85 | HDAC1 (0.39) | HRH4HRH3CNR2GBA1EPHX2 | |
| SCHEMBL12837588 | 0.84 | DYRK1A (0.34) | HRH4HRH3CNR2GBA1EPHX2 | |
| SCHEMBL12648625 | 0.81 | HDAC1 (0.37) | HRH4HRH3CNR2GBA1EPHX2 | |
| SCHEMBL12648628 | 0.81 | HDAC1 (0.36) | HRH4HRH3CNR2HDAC1DYRK1A | |
| Hydrochloric Acid SCHEMBL1523751 | 0.80 | HDAC1 (0.36) | HRH4HRH3CNR2GBA1EPHX2 | |
| Hydrochloric Acid SCHEMBL1524159 | 0.80 | HDAC1 (0.36) | HRH4HRH3CNR2HDAC1DYRK1A | |
| SCHEMBL12648622 | 0.80 | VIP (0.40) | HRH3HDAC1DYRK1ADYRK1B | |
| SCHEMBL12648620 | 0.80 | MIF (0.42) | HDAC1DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131654-A2 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-29 | — | — | WO | disclosed |