Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13667538 | 0.87 | HRH4 (0.36) | HDAC1 | |
| SCHEMBL12597864 | 0.83 | CBLB (0.38) | HDAC1HDAC3HDAC2ITGB3ITGA2B | |
| SCHEMBL13803814 | 0.83 | MAPT (0.34) | HDAC1HDAC3MAPTNPC1ALOX15 | |
| Hydrochloric Acid SCHEMBL1518079 | 0.83 | CBLB (0.37) | HDAC1HDAC3HDAC2ITGB3ITGA2B | |
| Dihydrosventrin SCHEMBL12559819 | 0.80 | CBLB (0.38) | HDAC1HDAC3HDAC2ITGB3ITGA2B | |
| Dihydrosventrin SCHEMBL1518647 | 0.79 | CBLB (0.38) | HDAC1HDAC3HDAC2ITGB3ITGA2B | |
| SCHEMBL13667359 | 0.78 | HDAC1 (0.34) | HDAC1HDAC3HDAC2ITGB3ITGA2B | |
| SCHEMBL12597863 | 0.75 | CBLB (0.39) | HDAC1HDAC3HDAC2MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL1518217 | 0.75 | CBLB (0.39) | HDAC1HDAC3HDAC2MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL1518082 | 0.74 | CBLB (0.39) | HDAC1HDAC3HDAC2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070304-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-06-04 | — | — | WO | disclosed |
| WO-2008094479-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-08-07 | — | — | WO | disclosed |