Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 18/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.44 |
| ▸ | ITGAL | P20701 | 18/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13668402 | 0.74 | ITGB2 (0.40) | ITGB2ICAM1ITGAL | |
| SCHEMBL20618448 | 0.65 | HDAC6 (0.40) | ITGB2ICAM1ITGALHDAC6 | |
| SCHEMBL27044200 | 0.65 | ITGB2 (0.59) | ITGB2ICAM1ITGAL | |
| SCHEMBL13894214 | 0.65 | ITGB2 (0.50) | ITGB2ICAM1ITGAL | |
| SCHEMBL4546546 | 0.65 | DRD2 (0.46) | ITGB2ICAM1ITGALHDAC6 | |
| SCHEMBL15445335 | 0.64 | HDAC6 (0.46) | ITGB2ICAM1ITGALHDAC6 | |
| SCHEMBL20618454 | 0.64 | HDAC6 (0.39) | ITGB2ICAM1ITGALHDAC6 | |
| SCHEMBL23978647 | 0.64 | ITGB2 (0.68) | ITGB2ICAM1ITGAL | |
| SCHEMBL26875017 | 0.64 | DRD2 (0.45) | ITGB2ICAM1ITGALHDAC6 | |
| SCHEMBL10129831 | 0.64 | ITGB2 (0.81) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128933-A1 | AEROSOLIZED LFA-1 ANTAGONISTS FOR USE IN LOCALIZED TREATMENT OF IMMUNE RELATED DISORDERS | SARCODE CORPORATION (US) | 2009-10-22 | — | — | WO | disclosed |