Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064091 | 0.87 | HTT (0.54) | HTTSMN1; SMN2TDP1L3MBTL1FFAR1 | |
| SCHEMBL13668496 | 0.84 | SMN1; SMN2 (0.46) | HTTSMN1; SMN2TDP1L3MBTL1FFAR1 | |
| SCHEMBL822840 | 0.83 | HTT (0.70) | HTTSMN1; SMN2TDP1L3MBTL1FFAR1 | |
| SCHEMBL13266193 | 0.83 | HTT (0.43) | HTTSMN1; SMN2TDP1L3MBTL1FFAR1 | |
| SCHEMBL13266187 | 0.82 | HTT (0.56) | HTTSMN1; SMN2TDP1L3MBTL1FFAR1 | |
| SCHEMBL9915246 | 0.82 | FFAR1 (0.42) | HTTSMN1; SMN2FFAR1KEAP1NFE2L2 | |
| SCHEMBL14036502 | 0.81 | GAA (0.50) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL13670309 | 0.80 | HTT (0.57) | HTTSMN1; SMN2TDP1L3MBTL1FFAR1 | |
| SCHEMBL13266243 | 0.79 | HTT (0.52) | HTTSMN1; SMN2TDP1L3MBTL1FFAR1 | |
| SCHEMBL16361395 | 0.79 | BCHE (0.48) | HTTSMN1; SMN2TDP1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253015-A1 | POLYARYLENE BLOCK COPOLYMER AND USE THEREOF | SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) | 2009-10-08 | — | — | US | disclosed |