Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.34 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13266193 | 0.96 | HTT (0.43) | SMN1; SMN2HTTTDP1L3MBTL1PTGS2 | |
| SCHEMBL2754676 | 0.92 | HTT (0.39) | SMN1; SMN2HTTTDP1L3MBTL1PTGS2 | |
| SCHEMBL13266251 | 0.87 | CNR2 (0.39) | SMN1; SMN2HTTPTGS2ALDH1A1PTGDR2 | |
| SCHEMBL822849 | 0.86 | HTT (0.61) | SMN1; SMN2HTTTDP1L3MBTL1PTGS2 | |
| SCHEMBL13668499 | 0.84 | HTT (0.50) | SMN1; SMN2HTTTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL10228504 | 0.83 | CNR2 (0.36) | SMN1; SMN2HTTPTGS2ALDH1A1PTGDR2 | |
| SCHEMBL10034487 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTTDP1L3MBTL1PTGS2 | |
| SCHEMBL13670320 | 0.83 | HTT (0.52) | SMN1; SMN2HTTTDP1L3MBTL1PTGS2 | |
| SCHEMBL12927418 | 0.82 | SLC6A9 (0.39) | SMN1; SMN2HTTTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL10018170 | 0.82 | HTT (0.56) | SMN1; SMN2HTTTDP1L3MBTL1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253015-A1 | POLYARYLENE BLOCK COPOLYMER AND USE THEREOF | SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) | 2009-10-08 | — | — | US | disclosed |