Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | CDC25A | P30304 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 9/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13852396 | 1.00 | CYP19A1 (0.49) | CYP19A1CDC25ACDC25BVDRHDAC6 | |
| SCHEMBL9010441 | 1.00 | CYP19A1 (0.49) | CYP19A1CDC25ACDC25BVDRHDAC6 | |
| SCHEMBL12464968 | 1.00 | CYP19A1 (0.49) | CYP19A1CDC25ACDC25BVDRHDAC6 | |
| SCHEMBL10125598 | 0.84 | CDC25A (0.46) | CYP19A1CDC25ACDC25BVDRHDAC6 | |
| SCHEMBL814645 | 0.84 | CDC25A (0.46) | CYP19A1CDC25ACDC25BVDRHDAC6 | |
| SCHEMBL17354893 | 0.84 | CYP19A1 (0.45) | CYP19A1CDC25ACDC25BVDRHDAC6 | |
| SCHEMBL3516877 | 0.84 | CYP19A1 (0.45) | CYP19A1CDC25ACDC25BVDRHDAC6 | |
| SCHEMBL3516879 | 0.84 | CYP19A1 (0.45) | CYP19A1CDC25ACDC25BVDRHDAC6 | |
| SCHEMBL9010563 | 0.84 | CYP19A1 (0.45) | CYP19A1CDC25ACDC25BVDRHDAC6 | |
| SCHEMBL20243735 | 0.84 | CYP19A1 (0.45) | CYP19A1CDC25ACDC25BVDRHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656157-B1 | 2-METHYLENE-19-NOR-VITAMIN D2 COMPOUNDS | WISCONSIN ALUMNI RES FOUND (US) | 2011-12-21 | — | — | EP | disclosed |
| US-7598408-B2 | Intermediates for synthesis of vitamin D derivatives | KNC LABORATORIES CO., LTD. (JP) | 2009-10-06 | — | — | US | disclosed |
| US-7232810-B2 | 2-methylene-19-nor-vitamin D2 compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-06-19 | — | — | US | disclosed |
| US-7232810-B2 | 2-methylene-19-nor-vitamin D2 compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-06-19 | — | — | US | disclosed |
| US-7208484-B2 | Method of synthesizing 1alpha-hydroxy-2-methylene-19-nor-homopregnacalciferol | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-04-24 | — | — | US | disclosed |
| US-7208484-B2 | Method of synthesizing 1alpha-hydroxy-2-methylene-19-nor-homopregnacalciferol | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-04-24 | — | — | US | disclosed |