Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26307074 | 0.96 | ALDH1A1 (0.39) | TSHRCYP11B1CYP11B2MAPTALDH1A1 | |
| SCHEMBL13152150 | 0.96 | ALDH1A1 (0.39) | TSHRCYP11B1CYP11B2MAPTALDH1A1 | |
| SCHEMBL14786665 | 0.94 | TSHR (0.46) | TSHRCYP11B1CYP11B2MAPTALDH1A1 | |
| SCHEMBL29338832 | 0.91 | CYP11B1 (0.50) | TSHRCYP11B1CYP11B2MAPTALDH1A1 | |
| SCHEMBL29338833 | 0.91 | CYP11B1 (0.50) | TSHRCYP11B1CYP11B2MAPTALDH1A1 | |
| SCHEMBL24715363 | 0.91 | MAPT (0.39) | TSHRCYP11B1CYP11B2MAPTALDH1A1 | |
| SCHEMBL8852754 | 0.91 | ALDH1A1 (0.43) | TSHRMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL14506990 | 0.87 | ALDH1A1 (0.46) | TSHRMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL17841771 | 0.87 | ALDH1A1 (0.46) | TSHRMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL11898477 | 0.87 | ALDH1A1 (0.46) | TSHRMAPTALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598010-B2 | Triarylamine dimer derivative having amorphous phase | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 2009-10-06 | — | — | US | disclosed |
| US-7598010-B2 | Triarylamine dimer derivative having amorphous phase | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 2009-10-06 | — | — | US | disclosed |