Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 12/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | CPT1A | P50416 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001170 | 1.00 | RORC (0.46) | RORCCNR1CNR2CPT1ACHRM1 | |
| SCHEMBL13669916 | 0.98 | RORC (0.46) | RORCCNR1CNR2CPT1ACHRM1 | |
| SCHEMBL12570206 | 0.98 | RORC (0.46) | RORCCNR1CNR2CPT1ACHRM1 | |
| SCHEMBL1999541 | 0.98 | RORC (0.46) | RORCCNR1CNR2CPT1ACHRM1 | |
| SCHEMBL2002936 | 0.98 | RORC (0.46) | RORCCNR1CNR2CPT1ACHRM1 | |
| SCHEMBL12570237 | 0.98 | RORC (0.46) | RORCCNR1CNR2CPT1ACHRM1 | |
| SCHEMBL2006856 | 0.98 | RORC (0.46) | RORCCNR1CNR2CPT1ACHRM1 | |
| SCHEMBL2001759 | 0.88 | RORC (0.49) | RORCCNR1CNR2CPT1AKMT2A | |
| SCHEMBL2000252 | 0.86 | RORC (0.47) | RORCCNR1CNR2CPT1AKMT2A | |
| SCHEMBL2000254 | 0.86 | RORC (0.47) | RORCCNR1CNR2CPT1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120660-A2 | SUBSTITUTED PYRIDOXAZINES | CARA THERAPEUTICS, INC. (US) | 2009-10-01 | — | — | WO | disclosed |