SCHEMBL13670313

SCHEMBL13670313

CCc1ccc(C(=O)c2ccc(Oc3ccc(C(=O)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
LMNA P02545 2/20 0.55
SRD5A2 P31213 6/20 0.53
MMP13 P45452 3/20 0.53
MAPK14 Q16539 2/20 0.52
P2RY14 Q15391 1/20 0.50
MAOB P27338 1/20 0.49
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49
HTT P42858 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
MMP2 P08253 1/20 0.48
CYP3A4 P08684 1/20 0.48
STAT3 P40763 1/20 0.48
PARP10 Q53GL7 1/20 0.47
KMT2A Q03164 2/20 0.47
MAPK1 P28482 1/20 0.47
MEN1 O00255 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13670310 1.00 ALDH1A1 (0.55) ALDH1A1LMNASRD5A2MMP13MAPK14
SCHEMBL19339947 1.00 ALDH1A1 (0.55) ALDH1A1LMNASRD5A2MMP13MAPK14
SCHEMBL18661573 1.00 ALDH1A1 (0.55) ALDH1A1LMNASRD5A2MMP13MAPK14
SCHEMBL16995928 1.00 ALDH1A1 (0.55) ALDH1A1LMNASRD5A2MMP13MAPK14
SCHEMBL13670325 0.95 ALDH1A1 (0.50) ALDH1A1LMNASRD5A2MMP13MAPK14
SCHEMBL13670306 0.92 P2RY14 (0.48) ALDH1A1LMNASRD5A2MMP13MAPK14
SCHEMBL13221965 0.92 ALDH1A1 (0.47) ALDH1A1LMNASRD5A2MMP13MAPK14
SCHEMBL13670312 0.90 SMN1; SMN2 (0.55) ALDH1A1LMNASRD5A2MMP13MAPK14
SCHEMBL13670333 0.90 P2RY14 (0.46) ALDH1A1LMNASRD5A2MMP13MAPK14
SCHEMBL13670311 0.90 SMN1; SMN2 (0.55) ALDH1A1LMNASRD5A2MMP13MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090269645-A1 POLYMER, POLYMER ELECTROLYTE AND FUEL CELL USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-29 US disclosed