Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13670364 | 0.88 | CPT1A (0.40) | CPT1APOLBPTGER3HDAC3HDAC4 | |
| SCHEMBL2024952 | 0.85 | CPT1A (0.41) | CPT1AHPGDSPOLBMAPTMEN1 | |
| SCHEMBL2000503 | 0.84 | CPT1A (0.47) | CPT1AHPGDSPOLBMAPTHDAC3 | |
| SCHEMBL2001541 | 0.83 | CPT1A (0.46) | CPT1AHPGDSPOLBMAPTHDAC3 | |
| SCHEMBL1998249 | 0.83 | CPT1A (0.46) | CPT1AHPGDSPOLBMAPTHDAC3 | |
| SCHEMBL2003304 | 0.82 | CPT1A (0.47) | CPT1AHPGDSPOLBMEN1KMT2A | |
| SCHEMBL2000511 | 0.82 | HPGDS (0.42) | CPT1AHPGDSPOLBMAPTHDAC1 | |
| SCHEMBL15889723 | 0.81 | MEN1 (0.40) | CPT1APOLBPTGER3HDAC3HDAC4 | |
| SCHEMBL2006076 | 0.81 | CPT1A (0.47) | CPT1AHPGDS | |
| SCHEMBL2001654 | 0.81 | CPT1A (0.45) | CPT1AHPGDSPOLBMAPTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120660-A2 | SUBSTITUTED PYRIDOXAZINES | CARA THERAPEUTICS, INC. (US) | 2009-10-01 | — | — | WO | disclosed |