SCHEMBL1367098

SCHEMBL1367098

CCCCCC(=O)C(N)=O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.73
CES2 O00748 5/20 0.70
CES1 P23141 5/20 0.70
AKR1B1 P15121 1/20 0.52
PPARG P37231 6/20 0.50
PPARD Q03181 6/20 0.50
PPARA Q07869 6/20 0.50
HDAC11 Q96DB2 5/20 0.50
TSHR P16473 4/20 0.50
GPR84 Q9NQS5 4/20 0.50
ALDH1A1 P00352 2/20 0.50
TLR2 O60603 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
FABP4 P15090 2/20 0.50
PTPN1 P18031 2/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50
MEN1 O00255 1/20 0.50
ESR1 P03372 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5083248 0.97 FAAH (0.77) FAAHCES2CES1PPARGPPARD
SCHEMBL5126810 0.97 FAAH (0.77) FAAHCES2CES1PPARGPPARD
SCHEMBL29287856 0.97 FAAH (0.77) FAAHCES2CES1PPARGPPARD
SCHEMBL6344027 0.97 FAAH (0.77) FAAHCES2CES1PPARGPPARD
SCHEMBL609881 0.97 FAAH (0.77) FAAHCES2CES1PPARGPPARD
SCHEMBL8458168 0.97 FAAH (0.77) FAAHCES2CES1PPARGPPARD
SCHEMBL3950801 0.97 FAAH (0.77) FAAHCES2CES1PPARGPPARD
SCHEMBL6899719 0.97 FAAH (0.77) FAAHCES2CES1PPARGPPARD
SCHEMBL28767487 0.97 FAAH (0.77) FAAHCES2CES1PPARGPPARD
SCHEMBL16915217 0.97 FAAH (0.77) FAAHCES2CES1PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111937174-B Light-emitting film, organic electroluminescent element, and method for producing same 柯尼卡美能达株式会社 2023-12-05 CN disclosed
US-20200248041-A1 ACTIVATOR FOR ACCELERATED ADHESION DEVELOPMENT SIKA TECHNOLOGY AG (CH) 2020-08-06 US disclosed
EP-3688052-A1 ACTIVATOR FOR ACCELERATED ADHESION DEVELOPMENT Sika Technology AG (CH) 2020-08-05 EP disclosed
EP-2209473-B1 METHOD OF TREATING POLYCYSTIC KIDNEY DISEASES WITH CERAMIDE DERIVATIVES GENZYME CORP (US) 2017-11-22 EP disclosed
US-20110288070-A1 METHODS FOR TREATING COGNITIVE DISORDERS USING INHIBITORS OF HISTONE DEACETYLASE FMR LLC 2011-11-24 US disclosed
US-20070148185-A1 Novel therapeutic target for protozoal diseases VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY 2007-06-28 US disclosed
US-6225334-B1 AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-05-01 US disclosed
US-5221762-A Reacting a phenol with benzolactone compound; then phosgene or thionyl chloride; esterification with alcohol BASF AKTIENGESELLSCHAFT (DE) 1993-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288070-A1 METHODS FOR TREATING COGNITIVE DISORDERS USING INHIBITORS OF HISTONE DEACETYLASE HDAC1, HDAC5, HDAC2 FAAH 663/4885CES2 186/4885CES1 412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.