Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.56 |
| ▸ | CES1 | P23141 | 4/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5127510 | 1.00 | CES2 (0.56) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL1365133 | 1.00 | CES2 (0.56) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL25526352 | 1.00 | CES2 (0.56) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL13903246 | 1.00 | CES2 (0.56) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL5126821 | 1.00 | CES2 (0.56) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL1257720 | 1.00 | CES2 (0.56) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL4803397 | 1.00 | CES2 (0.56) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL4802270 | 1.00 | CES2 (0.56) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL20648076 | 1.00 | CES2 (0.56) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL2401194 | 1.00 | CES2 (0.56) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2209473-B1 | METHOD OF TREATING POLYCYSTIC KIDNEY DISEASES WITH CERAMIDE DERIVATIVES | GENZYME CORP (US) | 2017-11-22 | — | — | EP | disclosed |
| US-9783833-B2 | Biocatalytic methods to convert cyclohexane oxidation process waste streams to useful products | INVISTA NORTH AMERICA S.A.R.L. (US) | 2017-10-10 | — | — | US | disclosed |
| WO-2013151393-A1 | METHOD FOR PRODUCING MIDDLE-CHAIN Ω-HYDROXY FATTY ACIDS, ΑAND Ω-DICARBOXYLIC ACIDS, AND Ω-AMINO FATTY ACIDS FROM LONG-CHAIN FATTY ACIDS BY BIOTRANSFORMATION | 이화여자대학교 산학협력단 (KR) | 2013-10-10 | — | — | WO | disclosed |
| US-20110288070-A1 | METHODS FOR TREATING COGNITIVE DISORDERS USING INHIBITORS OF HISTONE DEACETYLASE | FMR LLC | 2011-11-24 | — | — | US | disclosed |
| EP-2006289-A1 | PYRAZOLE-TYPE CYANINE DYE | Wako Pure Chemical Industries, Ltd. (JP) | 2008-12-24 | — | — | EP | disclosed |
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288070-A1 | METHODS FOR TREATING COGNITIVE DISORDERS USING INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC5, HDAC2 | CES2 186/4885CES1 412/4885GPR84 3717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.