Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 14/20 | 1.00 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.55 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13671333 | 0.91 | TRPA1 (0.83) | TRPA1PORCNTRPV4RORC | |
| SCHEMBL13671583 | 0.91 | TRPA1 (0.83) | TRPA1PORCNTRPV4 | |
| SCHEMBL13671336 | 0.91 | TRPA1 (0.83) | TRPA1PORCNTRPV4 | |
| SCHEMBL13671341 | 0.88 | TRPA1 (1.00) | TRPA1PORCNTRPV4 | |
| SCHEMBL13671690 | 0.88 | TRPA1 (0.79) | TRPA1PORCNTRPV4 | |
| SCHEMBL13671351 | 0.83 | TRPA1 (1.00) | TRPA1TRPV4 | |
| SCHEMBL13671584 | 0.83 | TRPA1 (1.00) | TRPA1PORCNTRPV4 | |
| SCHEMBL13671398 | 0.82 | TRPA1 (0.70) | TRPA1PORCNMAPTRORC | |
| SCHEMBL13671680 | 0.81 | TRPA1 (0.78) | TRPA1PORCNTRPV4 | |
| SCHEMBL13671692 | 0.81 | TRPA1 (0.68) | TRPA1PORCNMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118596-A2 | PHTHALIMIDE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS, S. A. (CH) | 2009-10-01 | — | — | WO | disclosed |