Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13673546 | 1.00 | KMT2A (0.52) | KMT2AMAPTALDH1A1HTTTDP1 | |
| Hydrochloric Acid SCHEMBL915076 | 0.99 | KMT2A (0.51) | KMT2AMAPTALDH1A1HTTTDP1 | |
| Hydrochloric Acid SCHEMBL915075 | 0.99 | KMT2A (0.51) | KMT2AMAPTALDH1A1HTTTDP1 | |
| SCHEMBL4701661 | 0.88 | KMT2A (0.54) | KMT2AMAPTALDH1A1HTTTDP1 | |
| SCHEMBL4701658 | 0.88 | KMT2A (0.54) | KMT2AMAPTALDH1A1HTTTDP1 | |
| SCHEMBL915572 | 0.87 | ALDH1A1 (0.47) | KMT2AMAPTALDH1A1HTTTDP1 | |
| SCHEMBL915573 | 0.87 | ALDH1A1 (0.47) | KMT2AMAPTALDH1A1HTTTDP1 | |
| SCHEMBL13674689 | 0.87 | MAPT (0.47) | KMT2AMAPTALDH1A1HTTTDP1 | |
| SCHEMBL13674690 | 0.87 | MAPT (0.47) | KMT2AMAPTALDH1A1HTTTDP1 | |
| SCHEMBL13673630 | 0.86 | GUSB (0.47) | KMT2AMAPTALDH1A1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410174-B2 | Method for treating arthritis | ANAMAR AB (SE) | 2013-04-02 | — | — | US | disclosed |
| US-8309609-B2 | Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands | ANAMAR AB (SE) | 2012-11-13 | — | — | US | disclosed |