Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13673619 | 1.00 | ALDH1A1 (0.62) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL915919 | 0.89 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL915920 | 0.89 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7748699 | 0.87 | ALDH1A1 (0.63) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7748695 | 0.87 | ALDH1A1 (0.63) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL5570018 | 0.85 | MAPT (0.50) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL5570016 | 0.85 | MAPT (0.50) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11772226 | 0.84 | MAPT (0.61) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11772236 | 0.84 | MAPT (0.61) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL915504 | 0.84 | MAPT (0.49) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410174-B2 | Method for treating arthritis | ANAMAR AB (SE) | 2013-04-02 | — | — | US | disclosed |
| US-8309609-B2 | Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands | ANAMAR AB (SE) | 2012-11-13 | — | — | US | disclosed |