Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 10/20 | 0.49 |
| ▸ | AR | P10275 | 7/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.49 |
| ▸ | VDR | P11473 | 8/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395685 | 1.00 | HDAC3 (0.63) | HDAC3HDAC6ESR1ARESR2 | |
| SCHEMBL16183054 | 0.90 | HDAC3 (0.65) | HDAC3HDAC6ESR1ARESR2 | |
| SCHEMBL15076977 | 0.85 | HDAC3 (0.71) | HDAC3HDAC6ARVDR | |
| SCHEMBL3421889 | 0.84 | HDAC3 (0.64) | HDAC3HDAC6ARVDR | |
| SCHEMBL16183052 | 0.82 | HDAC3 (0.73) | HDAC3HDAC6ARVDR | |
| SCHEMBL3393099 | 0.82 | HDAC3 (0.66) | HDAC3HDAC6ARVDR | |
| SCHEMBL13366655 | 0.82 | HDAC3 (0.61) | HDAC3HDAC6VDR | |
| SCHEMBL13675284 | 0.81 | HDAC3 (0.60) | HDAC3HDAC6ARVDR | |
| SCHEMBL3394913 | 0.81 | HDAC3 (0.68) | HDAC3HDAC6ARVDR | |
| SCHEMBL13672785 | 0.81 | HDAC3 (0.68) | HDAC3HDAC6ARVDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601850-B2 | less hypercalcemic than 1a,25 dihydroxy vitamin D3; bone disorders, psoriasis | ELI LILLY AND COMPANY (US) | 2009-10-13 | — | — | US | disclosed |