Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13674873 | 0.88 | F10 (0.41) | F10KCNH2 | |
| SCHEMBL13674854 | 0.85 | F10 (0.45) | F10KCNH2 | |
| SCHEMBL13675102 | 0.84 | F10 (0.46) | F10KCNH2 | |
| SCHEMBL4480807 | 0.82 | F10 (0.58) | F10 | |
| SCHEMBL13675120 | 0.79 | CYP1A2 (0.45) | F10KCNH2 | |
| SCHEMBL3552468 | 0.72 | F10 (0.41) | F10KCNH2 | |
| SCHEMBL13674871 | 0.72 | F10 (0.59) | F10 | |
| SCHEMBL3447396 | 0.71 | F10 (0.52) | F10 | |
| SCHEMBL13672265 | 0.71 | F10 (0.71) | F10 | |
| SCHEMBL4485097 | 0.71 | F10 (0.71) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601752-B2 | Pyrrolidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-10-13 | — | — | US | disclosed |