Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 2/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13474635 | 0.86 | LPL (0.38) | LPLLIPGCA12CA2CA3 | |
| SCHEMBL13100187 | 0.80 | — | — | |
| SCHEMBL2756805 | 0.80 | LPL (0.50) | ESR2LPLLIPGCA12CA2 | |
| SCHEMBL13186080 | 0.80 | LPL (0.34) | LPLLIPG | |
| SCHEMBL13509394 | 0.80 | LPL (0.34) | LPLLIPG | |
| SCHEMBL14231975 | 0.78 | LPL (0.51) | LPLLIPG | |
| SCHEMBL13217765 | 0.78 | LPL (0.33) | LPLLIPG | |
| SCHEMBL12512630 | 0.78 | LPL (0.33) | LPLLIPG | |
| SCHEMBL10085659 | 0.78 | LPL (0.33) | LPLLIPGCA12CA2CA3 | |
| SCHEMBL12189218 | 0.78 | CYP19A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605155-B2 | Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors | SCHERING CORPORATION (US) | 2009-10-20 | — | — | US | disclosed |