Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | PPM1B | O75688 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3257710 | 1.00 | ALDH1A1 (0.59) | ALDH1A1NPC1POLBGAAMAPK1 | |
| SCHEMBL26811910 | 1.00 | ALDH1A1 (0.59) | ALDH1A1NPC1POLBGAAMAPK1 | |
| SCHEMBL13871579 | 1.00 | ALDH1A1 (0.59) | ALDH1A1NPC1POLBGAAMAPK1 | |
| SCHEMBL17822523 | 1.00 | ALDH1A1 (0.59) | ALDH1A1NPC1POLBGAAMAPK1 | |
| SCHEMBL7257546 | 1.00 | ALDH1A1 (0.59) | ALDH1A1NPC1POLBGAAMAPK1 | |
| SCHEMBL7892319 | 1.00 | ALDH1A1 (0.59) | ALDH1A1NPC1POLBGAAMAPK1 | |
| SCHEMBL24538823 | 0.89 | HPGD (0.58) | ALDH1A1NPC1POLBGAAMAPK1 | |
| SCHEMBL20444806 | 0.89 | ALDH1A1 (0.58) | ALDH1A1NPC1POLBGAAMAPK1 | |
| SCHEMBL22799620 | 0.85 | ALDH1A1 (0.65) | ALDH1A1NPC1POLBGAAMAPK1 | |
| SCHEMBL22799371 | 0.85 | ALDH1A1 (0.65) | ALDH1A1NPC1POLBGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601820-B2 | Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives | PHARMASSET, INC. (US) | 2009-10-13 | — | — | US | disclosed |