Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329826 | 0.88 | ALOX12 (0.58) | ALOX12ALOX15CYP19A1ESR1ESR2 | |
| SCHEMBL330473 | 0.85 | ALOX12 (0.48) | ALOX12ALOX15GAAMAPTCYP19A1 | |
| SCHEMBL2071244 | 0.83 | ALOX12 (0.64) | ALOX12ALOX15POLBMAPTRECQL | |
| SCHEMBL3063910 | 0.78 | ALOX12 (0.68) | ALOX12ALOX15KDM4EPOLBALPI | |
| SCHEMBL30851585 | 0.78 | ALOX12 (0.68) | ALOX12ALOX15KDM4EPOLBALPI | |
| SCHEMBL19472344 | 0.78 | CYP19A1 (0.56) | ALOX12ALOX15KDM4EPOLBALPI | |
| SCHEMBL13840362 | 0.75 | CYP19A1 (0.66) | ALOX12ALOX15CYP19A1 | |
| SCHEMBL17938825 | 0.74 | ALOX12 (0.62) | ALOX12ALOX15KDM4EPOLBALPI | |
| SCHEMBL13673327 | 0.73 | CYP19A1 (0.57) | ALOX12ALOX15CYP19A1 | |
| SCHEMBL14184743 | 0.72 | ALOX12 (0.59) | ALOX12ALOX15CYP19A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601855-B2 | anticancer agents; chemotherapeutic selective agents | NOVOGEN RESEARCH PTY LTD (AU) | 2009-10-13 | — | — | US | disclosed |