Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334126 | 0.88 | PARP1 (0.55) | KMT2AMEN1PARP1HSD17B1HSD17B2 | |
| SCHEMBL16015484 | 0.86 | KMT2A (0.55) | KMT2AMEN1PARP1HSD17B1HSD17B2 | |
| SCHEMBL14117419 | 0.86 | KMT2A (0.58) | KMT2AMEN1PARP1HSD17B1HSD17B2 | |
| SCHEMBL15676740 | 0.82 | KMT2A (0.59) | KMT2AMEN1PPARGL3MBTL1CDK4 | |
| SCHEMBL22352079 | 0.82 | MEN1 (0.48) | KMT2AMEN1PARP1HSD17B1HSD17B2 | |
| SCHEMBL16900522 | 0.81 | MEN1 (0.50) | KMT2AMEN1PARP1HSD17B1HSD17B2 | |
| SCHEMBL16015427 | 0.80 | KMT2A (0.49) | KMT2AMEN1PARP1HSD17B1HSD17B2 | |
| SCHEMBL22753452 | 0.80 | MEN1 (0.46) | KMT2AMEN1PARP1HSD17B1HSD17B2 | |
| SCHEMBL322040 | 0.79 | KMT2A (0.53) | KMT2AMEN1HSD17B1HSD17B2CNR2 | |
| SCHEMBL15108901 | 0.79 | KMT2A (0.58) | KMT2AMEN1HSD17B1HSD17B2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270381-A1 | Non-steroidal progesterone receptor modulators | BAYER SCHERING PHARMA AG (DE) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270381-A1 | Non-steroidal progesterone receptor modulators | PGR, PGRMC1, PGRMC2 | KMT2A 1622/4885MEN1 2323/4885PARP1 2340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.