Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19334564 | 0.85 | MAPT (0.53) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13675804 | 0.80 | CA1 (0.41) | MAPTHTTCYP3A4GAALMNA | |
| SCHEMBL13675810 | 0.80 | CA1 (0.41) | MAPTHTTCYP3A4GAALMNA | |
| SCHEMBL10597302 | 0.79 | MAPT (0.47) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7557585 | 0.79 | MAPT (0.47) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL26049084 | 0.76 | HTT (0.37) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7559035 | 0.76 | MAPT (0.44) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7562816 | 0.76 | MAPT (0.44) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11782136 | 0.75 | MAPT (0.43) | MAPTHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7025738 | 0.73 | CYP3A4 (0.57) | MAPTHTTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601842-B2 | Method for producing an optically active tetrahydroquinoline | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-13 | — | — | US | disclosed |