Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13675810 | 1.00 | CA1 (0.41) | CA1CA12MMP8ALDH1A1TDP1 | |
| SCHEMBL13675540 | 0.84 | HTT (0.44) | CA1CA12MMP8ALDH1A1TDP1 | |
| SCHEMBL13675543 | 0.84 | HTT (0.44) | CA1CA12MMP8ALDH1A1TDP1 | |
| SCHEMBL13675812 | 0.84 | TDP1 (0.41) | CA1CA12ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL13675808 | 0.84 | TDP1 (0.41) | CA1CA12ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL13675541 | 0.80 | MAPT (0.43) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL13675809 | 0.78 | ALDH1A1 (0.47) | CA1CA12MMP8ALDH1A1TDP1 | |
| SCHEMBL13675805 | 0.78 | ALDH1A1 (0.47) | CA1CA12MMP8ALDH1A1TDP1 | |
| SCHEMBL13675817 | 0.76 | CA1 (0.42) | CA1CA12MMP8TDP1SMN1; SMN2 | |
| SCHEMBL13675539 | 0.76 | CA1 (0.42) | CA1CA12MMP8TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601842-B2 | Method for producing an optically active tetrahydroquinoline | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-13 | — | — | US | disclosed |