Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 20/20 | 0.88 |
| ▸ | DHFR | P00374 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635041 | 0.94 | GHSR (1.00) | GHSRDHFR | |
| SCHEMBL3633278 | 0.90 | GHSR (1.00) | GHSRDHFR | |
| SCHEMBL2669496 | 0.90 | GHSR (1.00) | GHSRDHFR | |
| SCHEMBL3632090 | 0.88 | GHSR (1.00) | GHSRDHFR | |
| SCHEMBL3636847 | 0.88 | GHSR (1.00) | GHSRDHFR | |
| SCHEMBL3632096 | 0.88 | GHSR (1.00) | GHSRDHFR | |
| SCHEMBL6363980 | 0.87 | GHSR (1.00) | GHSRDHFR | |
| SCHEMBL6360411 | 0.86 | GHSR (0.84) | GHSRDHFR | |
| SCHEMBL6364725 | 0.86 | GHSR (0.84) | GHSRDHFR | |
| SCHEMBL3636675 | 0.86 | GHSR (0.85) | GHSRDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024338-B1 | 4,5-DIPHENYL-PYRIMIDINYL SUBSTITUTED CARBOXYLIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | SANOFI AVENTIS (FR) | 2009-09-02 | — | — | EP | disclosed |