Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A1 | P53985 | 7/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829699 | 0.85 | SLC16A1 (0.59) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL4803812 | 0.84 | SLC16A1 (0.61) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL4802452 | 0.80 | SLC16A1 (0.80) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL14139859 | 0.78 | SLC16A1 (0.57) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL14099967 | 0.76 | SLC16A1 (0.59) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL4801966 | 0.75 | SLC16A1 (0.75) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL3829224 | 0.73 | SLC16A1 (0.76) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL5791248 | 0.73 | SLC16A1 (0.63) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL3829809 | 0.73 | SLC16A1 (0.78) | SLC16A1CYP2C9CYP3A4ABCB11 | |
| SCHEMBL3827135 | 0.72 | SLC16A1 (0.61) | SLC16A1CYP2C9CYP3A4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414825-B9 | THIENOPYRIMIDINEDIONES AND THEIR USE IN THE MODULATION OF AUTOIMMUNE DISEASE | ASTRAZENECA AB (SE) | 2009-09-16 | — | — | EP | disclosed |