Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.69 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 3/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 2/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13679716 | 0.91 | ABCB1 (0.84) | ABCB1NOX1ALOX5PTPN1MAPT | |
| SCHEMBL3829640 | 0.87 | ABCB1 (0.91) | ABCB1NOX1ALOX5PTPN1MAPT | |
| SCHEMBL13679717 | 0.87 | ABCB1 (0.91) | ABCB1NOX1ALOX5PTPN1MAPT | |
| SCHEMBL6625154 | 0.83 | ABCB1 (0.69) | ABCB1NOX1ALOX5PTPN1MAPT | |
| SCHEMBL3828912 | 0.83 | ABCB1 (0.69) | ABCB1NOX1ALOX5PTPN1MAPT | |
| SCHEMBL3826448 | 0.82 | ABCB1 (1.00) | ABCB1NOX1ALOX5PTPN1MAPT | |
| SCHEMBL719051 | 0.82 | ABCB1 (0.74) | ABCB1NOX1ALOX5PTPN1MAPT | |
| SCHEMBL719050 | 0.82 | ABCB1 (1.00) | ABCB1NOX1ALOX5PTPN1MAPT | |
| SCHEMBL30357745 | 0.80 | ABCB1 (0.87) | ABCB1NOX1ALOX5PTPN1MAPT | |
| SCHEMBL4442601 | 0.80 | ABCB1 (0.68) | ABCB1NOX1ALOX5PTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999835-B1 | IMIDAZOLE DERIVATIVES AS MDR MODULATORS | TAIJI BIOMEDICAL INC (US) | 2009-09-09 | — | — | EP | disclosed |