Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.87 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.35 |
| ▸ | GCGR | P47871 | 6/20 | 0.35 |
| ▸ | SELP | P16109 | 4/20 | 0.35 |
| ▸ | SELE | P16581 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | FRK | P42685 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826448 | 0.93 | ABCB1 (1.00) | ABCB1PTPN1MAPK13MAPK12MAPK11 | |
| SCHEMBL719050 | 0.93 | ABCB1 (1.00) | ABCB1PTPN1MAPK13MAPK12MAPK11 | |
| SCHEMBL719051 | 0.93 | ABCB1 (0.74) | ABCB1PTPN1MAPK13MAPK12MAPK11 | |
| SCHEMBL13679717 | 0.93 | ABCB1 (0.91) | ABCB1PTPN1MAPK13MAPK12MAPK11 | |
| SCHEMBL3829640 | 0.93 | ABCB1 (0.91) | ABCB1PTPN1MAPK13MAPK12MAPK11 | |
| SCHEMBL3824437 | 0.91 | ABCB1 (0.91) | ABCB1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL13679665 | 0.91 | ABCB1 (0.91) | ABCB1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL13679699 | 0.90 | ABCB1 (0.92) | ABCB1PTPN1MAPK13MAPK12MAPK11 | |
| SCHEMBL3830858 | 0.90 | ABCB1 (0.92) | ABCB1PTPN1MAPK13MAPK12MAPK11 | |
| SCHEMBL13780563 | 0.89 | ABCB1 (0.91) | ABCB1PTPN1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230111968-A1 | Secreted P-glycoprotein is a Non-Invasive Biomarker of Chronic Rhinosinusitis | MASSACHUSETTS EYE AND EAR INFIRMARY | 2023-04-13 | — | — | US | disclosed |