Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.91 |
| ▸ | MAPK13 | O15264 | 12/20 | 0.44 |
| ▸ | GCGR | P47871 | 12/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 12/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | FRK | P42685 | 2/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824437 | 1.00 | ABCB1 (0.91) | ABCB1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL3826448 | 0.95 | ABCB1 (1.00) | ABCB1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL719050 | 0.95 | ABCB1 (1.00) | ABCB1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL13679699 | 0.91 | ABCB1 (0.92) | ABCB1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL3830858 | 0.91 | ABCB1 (0.92) | ABCB1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL30357745 | 0.91 | ABCB1 (0.87) | ABCB1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL3829640 | 0.91 | ABCB1 (0.91) | ABCB1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL13780563 | 0.91 | ABCB1 (0.91) | ABCB1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL13679717 | 0.91 | ABCB1 (0.91) | ABCB1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL5468480 | 0.90 | ABCB1 (0.89) | ABCB1MAPK11MAPK14ALOX5CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999835-B1 | IMIDAZOLE DERIVATIVES AS MDR MODULATORS | TAIJI BIOMEDICAL INC (US) | 2009-09-09 | — | — | EP | disclosed |
| EP-2082740-A2 | Use of imidazole derivatives as MDR modulators | Taiji Biomedical, Inc. (US) | 2009-07-29 | — | — | EP | disclosed |