Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.67 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13679748 | 0.88 | ABCB1 (0.52) | ABCB1 | |
| SCHEMBL13679752 | 0.85 | ABCB1 (0.48) | ABCB1 | |
| SCHEMBL3827085 | 0.82 | ABCB1 (0.44) | ABCB1 | |
| SCHEMBL3827087 | 0.82 | ABCB1 (0.44) | ABCB1 | |
| SCHEMBL13679681 | 0.81 | ABCB1 (0.43) | ABCB1 | |
| SCHEMBL3826448 | 0.80 | ABCB1 (1.00) | ABCB1 | |
| SCHEMBL719050 | 0.80 | ABCB1 (1.00) | ABCB1 | |
| SCHEMBL13679704 | 0.79 | ABCB1 (0.42) | ABCB1 | |
| SCHEMBL3830858 | 0.77 | ABCB1 (0.92) | ABCB1 | |
| SCHEMBL13679699 | 0.77 | ABCB1 (0.92) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999835-B1 | IMIDAZOLE DERIVATIVES AS MDR MODULATORS | TAIJI BIOMEDICAL INC (US) | 2009-09-09 | — | — | EP | disclosed |
| EP-2082740-A2 | Use of imidazole derivatives as MDR modulators | Taiji Biomedical, Inc. (US) | 2009-07-29 | — | — | EP | disclosed |