Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12190636 | 0.80 | ANPEP (0.32) | ANPEPERAP1ERAP2ACP3ALDH1A1 | |
| SCHEMBL12549853 | 0.72 | PRSS1 (0.33) | ANPEPERAP1ERAP2 | |
| SCHEMBL15180672 | 0.69 | ANPEP (0.44) | ANPEPERAP1ERAP2ALDH1A1CYP1A2 | |
| SCHEMBL31303674 | 0.69 | ANPEP (0.44) | ANPEPERAP1ERAP2ALDH1A1CYP1A2 | |
| SCHEMBL12549185 | 0.69 | ANPEP (0.44) | ANPEPERAP1ERAP2ALDH1A1CYP1A2 | |
| SCHEMBL16490605 | 0.68 | ALDH1A1 (0.45) | ANPEPERAP1ERAP2ACP3ALDH1A1 | |
| SCHEMBL13680239 | 0.68 | ACP3 (0.36) | ANPEPERAP1ERAP2ACP3ALDH1A1 | |
| SCHEMBL9791568 | 0.67 | EPHX1 (0.45) | ANPEP | |
| SCHEMBL9791566 | 0.67 | EPHX1 (0.45) | ANPEP | |
| SCHEMBL28913527 | 0.67 | KCNH2 (0.44) | ANPEPERAP1ERAP2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582779-B2 | Processes and intermediates for the preparations of prostaglandins | CHIROGATE INTERNATIONAL INC. (TW) | 2009-09-01 | — | — | US | disclosed |