Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 15/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17215003 | 0.78 | SMN1; SMN2 (0.49) | GSK3BKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL18551784 | 0.74 | GSK3B (0.56) | GSK3BKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL23197679 | 0.73 | TDP1 (0.56) | GSK3BKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL13680470 | 0.72 | NPC1 (0.50) | NPC1GAA | |
| SCHEMBL18551785 | 0.72 | BRD4 (0.50) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13680599 | 0.72 | CA12 (0.54) | GSK3B | |
| SCHEMBL14138060 | 0.70 | FGFR1 (0.54) | GSK3BKDM4E | |
| SCHEMBL13680459 | 0.69 | APP (0.49) | GSK3BKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL2709215 | 0.68 | AHR (0.50) | GSK3BKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL17214829 | 0.68 | GSK3B (0.49) | GSK3BKDM4ENPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |