Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29963679 | 0.82 | MEN1 (0.68) | CYP2A6RAB9ANPC1NFKB1SMN1; SMN2 | |
| SCHEMBL647992 | 0.82 | MEN1 (0.68) | CYP2A6RAB9ANPC1NFKB1SMN1; SMN2 | |
| SCHEMBL16189026 | 0.81 | MEN1 (0.56) | CYP2A6RAB9ANPC1CCR1CCR8 | |
| SCHEMBL13680679 | 0.81 | CCR1 (0.60) | CYP2A6RAB9ACCR1CCR8TGFBR1 | |
| Bromide SCHEMBL15901554 | 0.81 | RAB9A (0.65) | CYP2A6RAB9ANPC1NFKB1SMN1; SMN2 | |
| SCHEMBL12594495 | 0.80 | MEN1 (0.64) | CYP2A6RAB9ANPC1CCR1CCR8 | |
| SCHEMBL17932287 | 0.80 | MEN1 (0.54) | CYP2A6RAB9ANPC1CCR1CCR8 | |
| SCHEMBL16189330 | 0.80 | MEN1 (0.54) | CYP2A6RAB9ANPC1CCR1CCR8 | |
| SCHEMBL16189443 | 0.80 | MEN1 (0.54) | CYP2A6RAB9ANPC1CCR1CCR8 | |
| SCHEMBL19009574 | 0.80 | MEN1 (0.47) | CYP2A6RAB9ANPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |