Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601756 | 0.81 | ATM (0.31) | ATM | |
| SCHEMBL13604502 | 0.81 | ATM (0.31) | ATM | |
| SCHEMBL13681759 | 0.81 | SLC6A2 (0.35) | — | |
| SCHEMBL11990382 | 0.76 | ACE (0.32) | ATM | |
| SCHEMBL8227865 | 0.75 | ACE (0.41) | — | |
| SCHEMBL11990391 | 0.75 | ACE (0.41) | — | |
| SCHEMBL85497 | 0.75 | ACE (0.41) | — | |
| SCHEMBL25728480 | 0.74 | CCR2 (0.38) | ATMALDH1A1 | |
| SCHEMBL10125636 | 0.74 | CCR2 (0.38) | ATMALDH1A1 | |
| SCHEMBL799809 | 0.74 | CCR2 (0.38) | ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585864-B2 | Farnesyl protein transferase inhibitors and their use to treat cancer | SCHERING CORPORATION (US) | 2009-09-08 | — | — | US | disclosed |