SCHEMBL13683245

SCHEMBL13683245

Sc1nnc(S)n1-c1cccc(NC2CC2)c1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.38
▸ MALT1 Q9UDY8 2/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ CSNK2A2 P19784 5/20 0.33
▸ ADORA2A P29274 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ KHK P50053 1/20 0.32
▸ NR3C1 P04150 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ PIM1 P11309 2/20 0.31
▸ VCP P55072 1/20 0.31
▸ DRD2 P14416 1/20 0.31
▸ DRD3 P35462 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14085438 0.80 CSNK2A2 (0.42) KDM4EMALT1SMN1; SMN2CSNK2A2L3MBTL1
SCHEMBL13867500 0.80 SMN1; SMN2 (0.45) KDM4EMALT1SMN1; SMN2CSNK2A2L3MBTL1
SCHEMBL14564587 0.77 TSHR (0.35) KDM4E
SCHEMBL14337668 0.73 ALDH1A1 (0.41) KDM4E
SCHEMBL14363437 0.73 POLB (0.33) KDM4E
SCHEMBL14093923 0.71 ALDH1A1 (0.50) SMN1; SMN2L3MBTL1
SCHEMBL13297738 0.70 POLB (0.42) SMN1; SMN2HTTLMNA
SCHEMBL14523039 0.70 MAPT (0.33) HTT
SCHEMBL14583724 0.67 TDP1 (0.49) KDM4EL3MBTL1LMNA
SCHEMBL6536863 0.67 ALDH1A1 (0.55) KDM4EL3MBTL1VCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7592133-B2 Silver halide photographic material and image forming method using the same FUJIFILM CORPORATION (JP) 2009-09-22 — — US disclosed
US-20080268385-A1 Silver halide photographic material and image forming method using the same FUJIFILM CORPORATION (JP) 2008-10-30 — — US disclosed
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