Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13685287 | 1.00 | APEX1 (0.32) | APEX1PTGS1AKR1C3 | |
| SCHEMBL13685319 | 0.79 | PTGS1 (0.30) | PTGS1AKR1C3 | |
| SCHEMBL13685320 | 0.79 | PTGS1 (0.30) | PTGS1AKR1C3 | |
| SCHEMBL8726421 | 0.76 | PTGS1 (0.37) | APEX1PTGS1AKR1C3 | |
| SCHEMBL8726425 | 0.76 | PTGS1 (0.37) | APEX1PTGS1AKR1C3 | |
| SCHEMBL13685272 | 0.76 | — | — | |
| SCHEMBL13685089 | 0.76 | PTGS1 (0.32) | PTGS1 | |
| SCHEMBL13685273 | 0.76 | — | — | |
| SCHEMBL3231458 | 0.76 | PTGS1 (0.32) | PTGS1 | |
| SCHEMBL8863667 | 0.74 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776399-B1 | MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS | UNIV GENT (BE) | 2012-11-14 | — | — | EP | claimed |