Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584637 | 0.95 | NPC1 (0.44) | NPY5RMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL2581890 | 0.94 | NPC1 (0.46) | NPY5RMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL2255388 | 0.83 | MAPT (0.60) | NPY5RMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL2580010 | 0.83 | CCNK (0.44) | NPY5RCCNKCDK9 | |
| SCHEMBL2585031 | 0.82 | CCNK (0.43) | NPY5RMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL13685290 | 0.80 | KMT2A (0.68) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL5131839 | 0.80 | CCNK (0.50) | NPY5RMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL1473954 | 0.79 | CSNK2A1 (0.54) | NPY5RMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL13685439 | 0.78 | RAB9A (0.57) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL13685464 | 0.78 | RAB9A (0.50) | MAPTKMT2ARAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101258131-B | As 5-HT2c6-aralkylamino-2 receptor agonists | LILLY CO ELI | 2013-07-24 | — | — | CN | disclosed |
| EP-1924561-B1 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | LILLY CO ELI (US) | 2012-11-14 | — | — | EP | disclosed |