Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 9/20 | 0.37 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | HTR2C | P28335 | 7/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15589945 | 0.81 | HTR2A (0.36) | HTR2BHTR2AHTR2CACACBPNMT | |
| SCHEMBL10230590 | 0.80 | HTR2A (0.37) | HTR2BHTR2AHTR2CMEN1RAB9A | |
| SCHEMBL506785 | 0.80 | HTR2A (0.43) | HTR2BHTR2AHTR2CKMT2APNMT | |
| SCHEMBL12175402 | 0.80 | HTR2B (0.43) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| SCHEMBL2585725 | 0.80 | HTR2B (0.39) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| SCHEMBL12175476 | 0.80 | HTR2B (0.44) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| SCHEMBL15589993 | 0.79 | HTR2A (0.36) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| Succinic Acid SCHEMBL2586811 | 0.79 | HTR2B (0.36) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| SCHEMBL2584623 | 0.79 | L3MBTL1 (0.35) | HTR2BHTR2AHTR2CGAAL3MBTL1 | |
| SCHEMBL16456573 | 0.79 | HTR2A (0.38) | HTR2BHTR2AHTR2CPNMTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924561-B1 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | LILLY CO ELI (US) | 2012-11-14 | — | — | EP | disclosed |