SCHEMBL13685403

SCHEMBL13685403

CCCc1c(OCCCCN2C(=O)NC(C)(c3cccnc3)C2=O)ccc2c(CF)cc(=O)oc12

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 20/20 0.67
NR1H3 Q13133 10/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1594073 0.89 NR1H2 (0.85) NR1H2NR1H3
SCHEMBL12727855 0.87 NR1H2 (0.80) NR1H2NR1H3
SCHEMBL1594113 0.80 NR1H2 (1.00) NR1H2NR1H3
SCHEMBL1593741 0.80 NR1H2 (0.98) NR1H2NR1H3
SCHEMBL6099746 0.79 NR1H2 (0.58) NR1H2NR1H3
SCHEMBL1594805 0.78 NR1H2 (0.95) NR1H2NR1H3
SCHEMBL1594215 0.77 NR1H2 (0.74) NR1H2NR1H3
SCHEMBL1595141 0.77 NR1H2 (0.86) NR1H2NR1H3
SCHEMBL12727747 0.77 NR1H2 (0.69) NR1H2NR1H3
SCHEMBL1593897 0.77 NR1H2 (0.84) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2248811-B1 2-OXOCHROMENE DERIVATIVE KOWA CO (JP) 2012-11-14 EP disclosed