SCHEMBL13685441

SCHEMBL13685441

Cc1c(Nc2ccc(N(C)CCS(C)(=O)=O)cc2F)ncnc1OC1CCN(C(=O)O)CC1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.58
CYP2C9 P11712 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL389476 0.91 GPR119 (0.73) GPR119CYP2C9
SCHEMBL3161254 0.86 GPR119 (0.59) GPR119CYP2C9
SCHEMBL6363097 0.85 GPR119 (0.60) GPR119CYP2C9
SCHEMBL389116 0.81 GPR119 (0.60) GPR119CYP2C9
SCHEMBL2783591 0.79 GPR119 (0.57) GPR119CYP2C9
SCHEMBL1071156 0.78 GPR119 (0.56) GPR119CYP2C9
SCHEMBL6361245 0.77 GPR119 (0.56) GPR119CYP2C9
SCHEMBL389304 0.77 GPR119 (0.77) GPR119CYP2C9
SCHEMBL390939 0.76 GPR119 (0.76) GPR119CYP2C9
SCHEMBL389551 0.76 GPR119 (0.76) GPR119CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1758565-B2 Method of identifying GLP-1 secretagogues ARENA PHARM INC (US) 2012-11-14 EP disclosed